2. シグナル伝達
  3. Epigenetics
  4. Histone Methyltransferase
  5. SETD7/KMT7 Isoform
  6. SETD7/KMT7 Inhibitor

SETD7/KMT7 Inhibitor

SETD7/KMT7 Inhibitors (3):

製品番号 製品名 製品効果 純度
  • HY-18627A
    PFI-2 hydrochloride Inhibitor 99.48%
    PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0  nM and (S)-PFI-2 shows inhibiting activity with IC50  value of 1.0  μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.
  • HY-18627
    PFI-2 Inhibitor 99.68%
    PFI-2 ((R)-PFI-2 hydrochloride) hydrochloride, a chemical probe, is a potent and selective SET domain containing lysine methyltransferase 7 (SETD7) inhibitor. (R)-PFI-2 shows high inhibiting activity with IC50 value of 2.0 nM and (S)-PFI-2 shows inhibiting activity with IC50 value of 1.0 μM. PFI-2 hydrochloride can be used for the research of chronic kidney disease and inflammation response in the development of renal fibrosis.
  • HY-119164
    DC-S238 Inhibitor
    DC-S238 is an orally active and highly selective histone methyltransferase SET7 (SETD7) inhibitor (IC50=4.88 μM). DC-S238 is promising for research of cancer, diabetes and inflammatory diseases.